How does chronic high blood sugar from diabetes damage the blood vessels and nerves that control the heart?
Chronic high blood sugar (hyperglycemia) from diabetes is highly destructive to the cardiovascular system because glucose, in excessive amounts, acts like a chemical corrosive. Instead of remaining cleanly inside your cells to be used for energy, excess glucose saturates the bloodstream, binding to proteins and fats and setting off a dual-pathway assault that damages both the physical plumbing (blood vessels) and the electrical control network (nerves) of the heart. 🩸 1. How High Blood Sugar Damages Blood Vessels The damage to blood vessels occurs at both the microscopic level (capillaries) and the structural level (major coronary arteries). This happens through three main chemical processes: A. Advanced Glycation End-products (AGEs) When glucose levels are high, sugar molecules randomly stick to proteins and fats in the bloodstream without an enzyme to guide them. This permanent chemical bonding creates toxic compounds called Advanced Glycation End-products (AGEs) . These AGE...